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CORNELL LABORATORY FOR ACCELERATOR-BASED SCIENCES AND EDUCATION

28 Aug 2018

Roadtrip to the BioCAT Beamline

Road trip!

<noautolink>Left to Right: Durgesh Rai, Susana Teixeira, Srinivas Chakravarthy, Richard Gillilan, and Jesse Hopkins.</noautolink>
Left to Right: Durgesh Rai, Susana Teixeira, Srinivas Chakravarthy, Richard Gillilan, and Jesse Hopkins.

CHESS postdoc Durgesh Rai and staff scientist Richard Gillilan joined Susana Teixeira (University of Delaware, NIST Center for Neutron Research) at the BioCAT beamline of the Advanced Photon Source in Chicago to study how proteins change under high pressure conditions.

Science has discovered vast habitats for organisms under extreme pressure, deep in the ocean and underground. In addition to shedding more light on the fundamental rules of life and the nature of protein folding, high pressure conditions have also proven valuable in pharma and food science.

<noautolink>New high pressure sample chamber.</noautolink>
New high pressure sample chamber.

The new high pressure sample chamber (circled in read), a collaboration between Cornell (Gruner group) and Pressure BioSciences Inc , will allow the future CHESS HP-Bio beamline to pressurize biological samples up to 7000 times atmospheric pressure ... the only such X-ray facility in the Western Hemisphere.

BioCAT staff scientists Jesse Hopkins and Srinivas Chakravarthy, who assisted, were both originally trained in X-ray scattering at CHESS.